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KLEE: After preseason Game 1, Broncos should take it easy with Manning

San Francisco 49ers running back LaMichael James, left, runs with the ball while pursued by Denver Broncos cornerback Omar Bolden, bottom, and linebacker Stewart Bradley (55) as linebacker Danny Trevathan (59) watches during the first quarter of an NFL preseason football game on Thursday, Aug. 8, 2013, in San Francisco. (AP Photo/Marcio Jose Sanchez)