DENVER - Jussi Jokinen skated across the front of the crease and roofed a shot over sprawling goalie Semyon Varlamov to give the Pittsburgh Penguins a 3-2 win over the Colorado Avalanche in a shootout Sunday.

After Jokinen's goal, Marc-Andre Fleury made a pad save on Gabriel Landeskog's shot, snapping Colorado's six-game win streak and denying Varlamov franchise records for home and overall season wins.

After falling behind 2-0 on Brandon Sutter's first multiple-goal game this season, Colorado scored twice in the third period to tie it and send the game to overtime.

Ryan O'Reilly scored his team-leading 28th goal of the season 18 seconds into the third period, and Patrick Bordeleau redirected defenseman Tyson Barrie's shot from the point past Fleury with 3:13 left.

Fleury had 39 saves, including one in the closing seconds of overtime after Penguins defenseman Paul Martin was sent to the penalty box with 37 seconds remaining for delay of game after he knocked the puck over the glass in the defensive zone.

Sutter scored his goals in the second period, one on a breakaway, the other on a power-play shot between Varlamov's legs.

Locked into the No. 2 seed in the Eastern Conference, the Penguins sat several of their regulars, including Sidney Crosby, who missed his first game of the season because of an unspecified injury.

Pittsburgh defensemen Brooks Orpik and Olli Maata and left wing Chris Kunitz also were scratched with unspecified injuries, and center Evgeni Malkin missed his eighth straight game due to a foot injury.

Varlamov finished 24-10-3 at home, matching Roy's 2000-01 record for home wins.

The Avalanche will finish the season with a four-game trip beginning Tuesday night at Edmonton. At 24-10-3, they own the best road-winning percentage (.689) in the NHL. Another win would break the franchise record for most road victories.

The Avs are two points ahead of Chicago (and have a game in hand) for second place in the Central Division, which would give them home-ice advantage in their first-round matchup in the playoffs. They trail St. Louis by four points.