SEATTLE - Denver defensive end Derek Wolfe has been placed on a backboard and taken away in an ambulance after sustaining a neck injury in the first quarter of a 40-10 preseason loss against the Seattle Seahawks.

Wolfe was hurt with 9 minutes left in the quarter and on Seattle's first offensive drive Saturday night. He was hurt being blocked on a running play where Seattle's Robert Turbin gained 8 yards. The Broncos said Wolfe was being evaluated for a cervical spine injury and had movement in all of his extremities.

Wolfe was initially cut on the play by Seattle's Luke Willson. As Wolfe was getting back up, fullback Michael Robinson collided with Wolfe appearing to compress his head and neck. Wolfe remained on the ground and appeared to be moving his legs initially, but medical personnel strapped him to a backboard and took him away in an ambulance.

He was down for about 8 minutes before being taken away.

Denver later saw starting right guard Louis Vasquez leave with a left knee injury.

Peyton Manning completed 11 of 16 passes for 163 yards and a touchdown to Wes Welker.

Seattle scored on two plays of more than 100 yards.

Jermaine Kearse returned a kickoff 107 yards after Welker's touchdown and defensive back Brandon Browner returned a fumble 106 yards for a score after a Ronnie Hillman fumble at the end zone. Kearse also caught a scoring pass from Seahawks second-year starter Russell Wilson, who shredded the Broncos' defense for two scores and 127 yards in the first half.

Denver tight end Julius Thomas had four catches for 70 yards, but he also fumbled.

Hillman, who is battling Montee Ball, gained 34 yards on 13 carries in the first half.

Denver's Von Miller, who could be suspended for the first four games of the season, had one tackle.